α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells.

Distribution and Relative Expression of Tight Junction Proteins in MODE-K Cells α-Chaconine concentration and incubation time had significant effects on the average immunofluorescence staining of tight junction proteins ZO-1 and occludin and the relative expression of tight junction protein ZO-1 in mouse intestinal epithelial cells, but the effect on the relative expression of the tight junction protein occludin did not reach statistical significance ( Table 6 and Supplementary Figure 1 ).

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