Tamoxifen treatment (1 mg/kg, i.p.) also modified daidzein hypolocomotion, although it did not reach statistical significance ( p = 0.084).
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Daidzein modulates cocaine-reinforcing effects and cue-induced cocaine reinstatement in CD-1 male mice.
2
0.0840
0.0840
The sentences
1 ), we investigated the involvement of the estrogen receptors (tamoxifen produced clear modulatory actions on daidzin locomotor effects that almost reached statistical significance, see Fig. 1e ) and DA D2/3 receptors in the modulatory effects induced by daidzein (isoflavone)s on cocaine reinforcement.