Molecular and Dynamic Evaluation of Proteins Related to Resistance to Neoadjuvant Treatment with Chemoradiotherapy in Circulating Tumor Cells of Patients with Locally Advanced Rectal Cancer.

Cells · 2021 · PMC8234587 · PMID 34207124

Europe PMC DOI

hedged sentences

0.3200

closest p · 6.4× alpha

0.3200

boldest claim

The sentences

showed a trendp = 0.32not close (p > 0.1)

The combined expression of PD-L1 in CTCs showed a trend to better DFS of 32.91 months for patients with positive expression for PD-L1 and 30.77 months for patients with no expression ( p = 0.32).

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may be significantno p-value reported

Thus, evaluating PD-L1 and TGF-β receptor I (TGF-βRI) expression during treatment may be significant for prognostic/prediction and better therapeutic definition.

also in 13,097 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.