Modified Hyaluronic Acid-Laminin-Hydrogel as Luminal Filler for Clinically Approved Hollow Nerve Guides in a Rat Critical Defect Size Model.

Adding cell-free 0.2% HA or 0.2% HAL [ 30 ] did clearly diminish recovery rates, while adding 0.4% or 0.7% M-HAL as luminal filler (current study) showed a trend of increasing TA muscle recovery rates over those achieved with empty nerve guides or CNG filled with cell-free 0.2% HA or 0.2% HAL.

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