Hepatitis B virus (HBV) viral load, liver and renal function in adults treated with tenofovir disoproxil fumarate (TDF) vs. untreated: a retrospective longitudinal UK cohort study.

BMC Infect Dis · 2021 · PMC8235844 · PMID 34174833

Europe PMC DOI

hedged sentences

0.2000

closest p · 4.0× alpha

0.2000

boldest claim

The sentences

did not reach statistical significancep = 0.2not close (p > 0.1)

However, the difference in progression between the two groups did not reach statistical significance (0/30 vs. 6/81, p = 0.2).

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borderline significantno p-value reported

One study carried out among CHB patients with high HBV DNA viral load (> 6 log 10 IU/ml) reported that TDF treatment was associated with a higher incidence of acute kidney injury (AKI) compared to ETV, but this difference was only borderline significant after three years follow-up [ 16 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.