Serum IGF1 and linear growth in children with congenital leptin deficiency before and after leptin substitution.

Int J Obes (Lond) · 2021 · PMC8236407 · PMID 34002033

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showed a trendno p-value reported

At T12, IGF1-SDS increased significantly (∆ T0–12 : 1.63 ± 1.40, p = 0.01), and IGFBP3-SDS and IGF1/IGFBP3 molar ratio-SDS showed a trend toward an increase.

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