Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events.

45 In both of these studies, the rate of recurrence was higher in patients who had initially experienced a grade ≥3 irAE, although this difference did not reach statistical significance. 44 45 A notable group of irAEs—myositis, myocarditis, and myasthenia gravis—are frequently seen in the same patients and deserve particular attention due to a high mortality rate.

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