Association between body mass index, dosing strategy, and efficacy of immune checkpoint inhibitors.

J Immunother Cancer · 2021 · PMC8237749 · PMID 34127546

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.1000

boldest claim

The sentences

a near significant trendp=0.08so close (0.05 < p ≤ 0.1)

In the weight-based dosing cohort, the difference in dose exposure was more pronounced and had a near significant trend (p=0.08).

also in 33 other papers

a near-significant trendp=0.1so close (0.05 < p ≤ 0.1)

There was no association between radiographic response and BMI with fixed-dose ICI (p=0.97), but a near-significant trend with weight-based ICI (p=0.1).

also in 290 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.