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A new antisarcoma strategy: multisubtype heat shock protein/peptide immunotherapy combined with PD-L1 immunological checkpoint inhibitors.

Clin Transl Oncol · 2021 · PMC8238772 · PMID 33792840

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showed a trendno p-value reported
IL-10 is a negative immunoregulatory cytokine for tumor immune escape, but it showed a trend of increased expression in these experiments.

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an increasing trendno p-value reported
With the increase in IFN-γ content in the local microenvironment, the expression of PD-L1 on the surface of tumor cells also showed an increasing trend [ 36 , 37 ].

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.