Thymic Epithelial Cell Alterations and Defective Thymopoiesis Lead to Central and Peripheral Tolerance Perturbation in MHCII Deficiency.

Front Immunol · 2021 · PMC8239840 · PMID 34211466

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showed a trendno p-value reported

Interestingly, we found that all four patients analyzed (three before and one after HSCT) showed a trend towards reduced expression of Vα7.2 on their CD3 + T cells as compared to normal controls tested in parallel (median: MHCII-D 2.1%; HD 6.8%) ( Figures 3E, F ).

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