Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements.

World J Gastroenterol · 2021 · PMC8240056 · PMID 34239263

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did not reach statistical significanceno p-value reported

A systematic review reported that tenofovir was associated with lower risk of HCC development [adjusted hazard ratio (HR) 0.81; 95%CI: 0.62-0.85], however the beneficial effect did not reach statistical significance for non-cirrhotic patients (adjusted HR 0.83; 95%CI: 0.51-1.35)[ 99 ].

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