Regular consumption of cod liver oil is associated with reduced basal and exercise-induced C-reactive protein levels; a prospective observational trial : A NEEDED (The North Sea Race Endurance Exercise Study) 2014 sub-study.

In multiple regression analysis, regular use of any omega-3 fatty acid supplements was associated with a 16% (95% confidence interval: − 28- -5%), p = 0.006 decrease in ln-transformed delta CRP level as compared to subjects who reported no or sporadic use of omega-3 fatty acid supplements (Table 3 , Model 4). There was a highly significant increase in creatine kinase values following the race ( p < 0.001), but no difference between the different categories of supplement users (Supplementary Figure 2 ).

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This analysis showed a borderline significant trend in lower CRP levels for the regular users of CLO (Supplementary Table 5 ).

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