Carbonate apatite nanoparticles carry siRNA(s) targeting growth factor receptor genes egfr1 and erbb2 to regress mouse breast tumor.

Drug Deliv · 2017 · PMC8240997 · PMID 29119846

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showed a trendno p-value reported

siRNA targeting egfr1 gene showed significant ( p = .03) decrease in viability and siRNA targeting erbb2 gene showed a trend in decreasing viability (statistically not significant) compared to respective NPs treatment, However, no improved outcome was observed for igf1r -targeting siRNA.

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