Antisense Inhibition of Angiotensinogen With IONIS-AGT-L<sub>Rx</sub>: Results of Phase 1 and Phase 2 Studies.

JACC Basic Transl Sci · 2021 · PMC8246029 · PMID 34222719

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did not reach statistical significanceno p-value reported

There was a nonsignificant larger reduction in SBP (−8 mm Hg; 95% CI: −17 to 2 mm Hg) or DBP (−1 mm Hg; 95% CI: −8 to 5 mm Hg) observed with IONIS-AGT-L Rx compared with placebo but these did not reach statistical significance.

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