In accordance with our results, the U-shaped association between age at menarche and risk of all-cause mortality were also observed in 2 previous studies and 2 meta-analyses, 5 , 6 , 8 , 9 whereas the HRs for participants with late age at menarche did not reach statistical significance.
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Joint Associations of Actual Age and Genetically Determined Age at Menarche With Risk of Mortality.
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