Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2.

Clin Pharmacol Ther · 2021 · PMC8247900 · PMID 33336382

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did not reach statistical significanceno p-value reported

Regarding the effect on the basal MR, CYP2C19 IM had the highest and RM the lowest values but this difference did not reach statistical significance due to the small number of subjects investigated ( Figure S4 ).

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