Barely Significant
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Aggregation is a Context-Dependent Constraint on Protein Evolution.

Front Mol Biosci · 2021 · PMC8249573 · PMID 34222334

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a clear trendno p-value reported
There is a clear trend toward a decrease of the AUC score (i.e., increase of 1-AUC) with the number of mutations and evolutionary cycles (generation).

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