Functional Genomic Analysis of a RUNX3 Polymorphism Associated With Ankylosing Spondylitis.

Arthritis Rheumatol · 2021 · PMC8251554 · PMID 33369221

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closest p · 1.6× alpha

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showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

ChIP‐qPCR analysis of freshly isolated CD8+ T cells from healthy donors heterozygous for rs4648889 also showed a trend toward enhanced enrichment of IRF5 for the protective G allele ( P = 0.08) (Figure 4E ).

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