The energy sensor AMPK orchestrates metabolic and translational adaptation in expanding T helper cells.

Of the 569 analyzed biochemicals, 80 were significantly less abundant in KO T cells with another 49 trending toward significance (ie, a p‐value between 0.05 and 0.10).

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Similarly, AMPK‐deficient pathogenic Th17 cell and immunosuppressive Treg populations showed a strong trend toward reduction at 6 weeks after transfer (Figure S2 C).

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