Chronic glucocorticoid treatment induces hepatic lipid accumulation and hyperinsulinaemia in part through actions on AgRP neurons.

Of note, throughout the GTT there was little change in the insulin levels in Cort treated AgRP-GR KO mice and although the mean levels of insulin in this group were around 5.8 fold higher than vehicle treated AgRP-GR KO animals, the difference did not reach statistical significance.

also in 111,027 other papers