Barely Significant
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A major QTL at the LHCGR/FSHR locus for multiple birth in Holstein cattle.

Genet Sel Evol · 2021 · PMC8255007 · PMID 34217202

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a positive trendno p-value reported
In the recent past, no clear genetic trend for the two studied traits (mbd and mbm) has been observed in the Swiss data in contrast to previous findings in Norwegian cattle [ 28 ] that showed a positive trend.

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a negative trendno p-value reported
Reports on the genetic trend for MBR are conflicting, with one study showing a negative trend over time [ 7 ] and another one finding no association between MBR and time [ 13 ].

also in 4,201 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.