GSK-3 Inhibition Modulates Metalloproteases in a Model of Lung Inflammation and Fibrosis.

Consistent with our IPF fibroblast studies, αSMA protein levels in MRC5 cells increased after TGFβ stimulation (2 and 5 ng/ml) and decreased after co-treatment with SB216763, although the decrease did not reach statistical significance ( Figure 6B ).

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