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Effects of Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction in Patients Undergoing Peritoneal Dialysis.

Front Med (Lausanne) · 2021 · PMC8255468 · PMID 34235161

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a notable trendno p-value reported
15/21, P = 0.021) were obviously alleviated, NYHA classification and E/e' ratio showed a notable trend of improvement after 3–12 months of follow-up.

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showed a trendno p-value reported
Cardiac diastolic function showed a trend of improvement, demonstrated as a lower ratio of E/e' after treatment with ARNI and decreased by 19% compared to before treatment, although we did not find statistically significant improvements in echocardiographic indicators associated with HFpEF (E/e', TR, and LVDd), which might be related to the small sample size and short follow-up time.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.