Barely Significant
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Rifampin Reduces the Plasma Concentrations of Oral and Intravenous Hydromorphone in Healthy Volunteers.

Anesth Analg · 2021 · PMC8257471 · PMID 33177323

Europe PMCDOI
1
hedged sentence
0.0579
closest p · 1.2× alpha
0.0579
boldest claim

The sentences

did not reach statistical significanceP = .0579so close (0.05 < p ≤ 0.1)
The C max of HM3G was 17% lower (ratio to control: 0.83, 90% CI, 0.71-0.97) in the rifampin phase compared with placebo, but this did not reach statistical significance ( P = .0579).

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