nominally significantp = 0.01
Phenotypic similarity analysis for locations within the NaV1.2 channel and recurrent variants Phenotypic similarity was nominally significant between individuals with missense variants regardless of location ( p = 0.01, n = 341) and also among individuals with missense variants localized to either the S1 segment ( p = 0.009, n = 18) or domain DIV ( p = 0.05, n = 65).