Structural basis of ethnic-specific variants of PAX4 associated with type 2 diabetes.

As suggested by a previous study 4 , most of these lead variants at T2D loci in either the Japanese or European population showed at least nominally significant ( P < 0.05) associations in the alternative population, even if not genome-wide significant, except for variants that were rare or monomorphic in one population such as NKX6-1 rs201597274, HNF1A rs187150787, and PAX4 rs2233580 in the Japanese population and HNF1A rs56348580 in the European population.

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