The effects of the addition of a new airway clearance device to chest physiotherapy in children with cystic fibrosis pulmonary exacerbations.

LCI also appears to worsen during cough episodes and pulmonary exacerbations in children with CF, but not in healthy children [ 28 ].In our study, the LCI showed a downward trend over time and reductions from baseline were clinically relevant, but LCI z -score decreases did not reach statistical significance in either group.

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