Fidgetin-like 2 negatively regulates axonal growth and can be targeted to promote functional nerve regeneration.

Recovery of nNOS in the corporal tissue at 1 month was less clear than in the crush study, but Western blot of penile shaft lysates from control animals and from the FL2-siRNA wafer–treated animals that exhibited bilateral CN regeneration showed a trend toward increased levels of nNOS ( Figure 7, G and H ).

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