C-peptide enhances glucagon secretion in response to hyperinsulinemia under euglycemic and hypoglycemic conditions.

JCI Insight · 2021 · PMC8262495 · PMID 34003799

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did not reach statistical significanceno p-value reported

Because of enhanced glucagon secretion in CPEP and the higher levels of glucagon in the hepatic sinusoids, net hepatic glucose uptake was somewhat lower in CPEP compared with SAL, although this did not reach statistical significance.

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