GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health.

Nat Commun · 2021 · PMC8263756 · PMID 34234147

Europe PMC DOI

hedged sentence

0.0200

closest p · 0.4× alpha

0.0200

boldest claim

The sentences

nominally significantp = 0.02actually significant

This single variant accounted for 76% of loss of function carriers and the CHEK2 association was nominally significant when it was excluded ( p = 0.02, effect = 0.18 SD).

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