5-aza-2'-deoxycitidine inhibits cell proliferation, extracellular matrix formation and Wnt/β-catenin pathway in human uterine leiomyomas.

Although the BAX/BCL2 ratio showed a trend to increase in HULP cells after treatment, no significant differences were observed with 2, 5, or 10 μM of 5-aza-CdR [fold change (FC) = 1.46, p -value = 0.099; FC = 1.54, p -value = 0.158; FC = 1.13, p -value = 0.099, respectively) compared to untreated cells (Fig. 2 D).

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