did not reach statistical significanceP = 0.0603
Although the difference did not reach statistical significance ( P = 0.0603) other authors have reported that early intubation may be associated with improved outcomes in patients with COVID-19. 9 Our patients were transitioned to APRV late in their hospital course, and although we did not observe any difference in the time of APRV implementation between survivors and non survivors, it remains unclear if APRV can improve clinical outcomes when used as a primary mode of ventilation.