An Evaluation of the Tolerability and Feasibility of Combining 5-Amino-Levulinic Acid (5-ALA) with BCNU Wafers in the Surgical Management of Primary Glioblastoma.

In exploratory analyses, there was strong evidence of longer OS in the total resection group compared with partial resection (HR = 0.47, 95% CI: 0.26–0.85, p = 0.01); the same direction of effect was also observed for PFS, although this did not reach statistical significance (HR = 0.63, 95% CI: 0.35–1.14, p = 0.12) ( Figure 3 ).

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