Combinations of Histone Deacetylase Inhibitors with Distinct Latency Reversing Agents Variably Affect HIV Reactivation and Susceptibility to NK Cell-Mediated Killing of T Cells That Exit Viral Latency.

Int J Mol Sci · 2021 · PMC8267728 · PMID 34206330

Europe PMC DOI

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0.0520

closest p · 1.0× alpha

0.0520

boldest claim

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nearly significantp = 0.052so close (0.05 < p ≤ 0.1)

On the other hand, NK-cell mediated viral suppression was 34 ± 7% in the presence of PRO (increased in 8/10 donors) and 37 ± 4% with ROM/PRO combination (increased in 7/10 donors), this latter being higher than in ROM-treated and untreated co-cultures in a statistically significant and nearly significant ( p = 0.052) manner, respectively ( Figure 5 B).

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