ADCC-Inducing Antibody Trastuzumab and Selection of KIR-HLA Ligand Mismatched Donors Enhance the NK Cell Anti-Breast Cancer Response.

Compared to normoxia, NK cell degranulation against SKBR3 was around 10% lower under hypoxic conditions, but this did not reach statistical significance, illustrating that degranulation levels of activated NK cells were not severely impaired by low oxygen ( Figure 1 D).

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