Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration.

Int J Mol Sci · 2021 · PMC8268331 · PMID 34202702

Europe PMC DOI

hedged sentence

0.1700

closest p · 3.4× alpha

0.1700

boldest claim

The sentences

failed to reach statistical significancep = 0.17not close (p > 0.1)

AMD-RPE cells showed a 3.6-fold higher baseline secretion of IL-1β even before inflammasome activation, though this increase failed to reach statistical significance due to high variability between independent repetitions of the experiment ( Figure 2 ; p = 0.17).

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