The Implications of Pruritogens in the Pathogenesis of Atopic Dermatitis.

Int J Mol Sci · 2021 · PMC8269281 · PMID 34281281

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In a phase 2a randomized double-blinded study, tezepelumab (AMG 157, MED19929), a humanized anti-TSLP antibody, showed a trend towards improvement in pruritus and severity of AD at week 16 in combination with topical corticosteroids (TCS) in moderate to severe AD [ 12 ].

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