Although our data only showed a trend towards better OS in the intermediate group, most patients now receive multiple post-progression treatments, including surgery, chemotherapy and biological-targeted therapies, which can significantly confound and dilute the effects of the time interval to chemotherapy on the OS endpoint.
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Impact of the Time Interval Between Primary Debulking Surgery and Start of Adjuvant Chemotherapy in Advanced Epithelial Ovarian Cancer.
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The sentences
In our entire cohort, we found a borderline significant of higher optimal debulking rate in the intermediate group.