Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer.

J Immunother Cancer · 2021 · PMC8276303 · PMID 34253638

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showed a trendno p-value reported

Although proportions of CD8 + T cells to CD4 + T cells did not show significant difference among the control, AB680, and PD-1 blocker-treated groups from our scRNA-seq results ( online supplemental figure 1a ), AB680 treatment showed a trend to increase ratio of CD8 + T cells to CD4 + T cells compared with the control group.

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