Inhibition of RPS6K reveals context-dependent Akt activity in luminal breast cancer cells.

PLoS Comput Biol · 2021 · PMC8277016 · PMID 34191793

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a clear trendno p-value reported

In fact, in the case of MCF7 cells, where the difference between the initial levels of pAKT elicited by IGF1 or Ins is not quite as big as in the other cell lines, a clear trend towards a further increase of pAKT after 30 minutes of IGF1 stimulation with S6K inhibition can be seen.

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