Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study.

Am J Obstet Gynecol · 2021 · PMC8278569 · PMID 33493488

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a clear trendno p-value reported

For BRCA1 mutation carriers, the association between ever use of oral contraceptives and risk of ovarian cancer did not show a clear trend according to age at first use of oral contraceptives (≤19 years [HR, 0.43; 95% CI, 0.28–0.65]; 20–23 years [HR, 0.51; 95% CI, 0.33–0.78]; >24 years [HR, 0.63; 95% CI, 0.41–0.97]; P trend =.15).

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