Genetic underpinnings of sociability in the general population.

Neuropsychopharmacology · 2021 · PMC8280100 · PMID 34054130

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

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The sentences

highly significantp = 3.6e−28actually significant

We found highly significant negative genetic correlations between sociability and ASDs ( r g = −0.27, p = 3.6e−28), MDD ( r g = −0.67, p = 4.5e−249), and SCZ ( r g = −0.15, p = 7.5e−23).

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nominally significantno p-value reported

Functional annotation and gene-mapping of genomic risk loci Functional annotation and gene-mapping of genomic risk loci was performed using the Functional Mapping and Annotation (FUMA) online tool, version v1.3.5e ( http://fuma.ctglab.nl [ 51 ]), including all nominally significant SNPs that were in LD ( r 2 ≥ 0.6) with one of the independent genome-wide significant SNPs from the sociability GWAS.

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