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Intracellular lipid droplet accumulation occurs early following viral infection and is required for an efficient interferon response.

Nat Commun · 2021 · PMC8280141 · PMID 34262037

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showed a trendno p-value reported
IFN mRNA levels showed a trend of returning to basal levels after 72 h.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.