Caloric intake was initially elevated in the OVX (7%, P < 0.05) and the HFD-OVX (8%, P < 0.01) groups, whereas the HFD did not reach statistical significance, when compared with lean-sham OVX (Fig. 1 B, D).
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Treatment with a dual amylin and calcitonin receptor agonist improves metabolic health in an old, obese, and ovariectomized rat model.
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