Modeling the selective advantage of new amino acids on the hemagglutinin of H1N1 influenza viruses using their patient age distributions.

Supplementary Fig S10 shows a clear trend that the fixation starts from old birth-year groups, followed by the middle-aged birth-year groups and ended with the young birth-year groups for all the nineteen fixed amino acids (see Section 2 for the definition of fixation in this study).

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