Myofibroblast transcriptome indicates SFRP2<sup>hi</sup> fibroblast progenitors in systemic sclerosis skin.

The larger subpopulation of cells (subcluster 0) included a subgrouping of cells, highly expressing CCL19 showing a strong trend toward more SSc fibroblasts (Fig. 3b ), the SSc CCL19 + fibroblasts clustering separately from the control CCL19 + fibroblasts (Fig. 2c ), expressing higher levels of CCL19 (Fig. 3a ) and localizing primarily perivascularly (Supplementary Fig. 4 ).

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