Impaired SNF2L Chromatin Remodeling Prolongs Accessibility at Promoters Enriched for Fos/Jun Binding Sites and Delays Granule Neuron Differentiation.

Similarly, we confirmed a ∼3-fold increase in expression of the Fosb (FC = 3.16, p = 0.035) and Fosl2 (FC = 2.79, p = 0.39) genes, although Fosl2 did not reach statistical significance ( Figure 3D ) in the Ex6DEL P10 cerebella, suggesting that the pathway was active both in vitro (isolated GNPs) and in vivo .

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