Patients with any positive autoimmune antibody (antiSOX2, anti-Hu, anti-Yo, anti-VGCCA, anti-VGPCA, antinuclear, or anti-neutrophil cytoplasmic antibodies) showed a trend for prolonged survival and better PFS in a study combining carboplatin plus etoposide with ipilimumab [ 36 ], but this assessment has not been included in other studies to explore its potential as a biomarker further.
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Evidence to Date: Evaluating Pembrolizumab in the Treatment of Extensive-Stage Small-Cell Lung Cancer.
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