showed a trendp = 0.134
Patients with overexpression (z-score >2) and/or amplification of group 3 TKs, which varied independent of molecular phenotype, showed a trend of worse median OS (30.91 vs. 59.26 mos., log-rank p = 0.134) and significantly worse median DFS (27.99 vs. 72.34 mos., log-rank p = 0.0391) than those without alteration (S2D Table in S1 File , Fig 2C ).