Effect of Liraglutide on Arterial Inflammation Assessed as [¹⁸F]FDG Uptake in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Trial.

In an exploratory analysis, we compared change in carotid [ 18 F]FDG uptake in participants with (n=23) and without (n=79) a history of CVD and we observed a borderline significant interaction ( P =0.052) between treatment group and history of CVD for predicting change in carotid [ 18 F]FDG uptake (Figure 4 ).

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When only including subjects with known CVD in the analysis (n=23), we observed a numeric difference in the reduction of [ 18 F]FDG uptake in subjects treated with liraglutide compared with placebo, but the difference did not reach statistical significance perhaps due to lack of power.

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